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Article

The role of KMT2 gene in human tumors.

Histology and histopathology - 1 Apr 2022

Zhang Zhi-Long, Yu Peng-Fei, Ling Zhi-Qiang

Abstract excerpt

Histone methylation plays a crucial role in the regulation of gene transcriptional expression, and aberration of methylation-modifying enzyme genes can lead to a variety of genetic diseases, including human cancers. The histone modified protein KMT2 (lysin methyltransferase) family are involved in cell proliferation, growth, development and differentiation through regulating gene expression, and are closely...

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PMID: 35233758
DOI: 10.14670/HH-18-447

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