Article
The role of protein methyltransferases as potential novel therapeutic targets in squamous cell carcinoma of the head and neck.
Oral oncology - 1 Jun 2018
Saloura Vassiliki, Vougiouklakis Theodore, Sievers Cem, Burkitt Kyunghee, Nakamura Yusuke, Hager Gordon, van Waes Carter
Abstract excerpt
Squamous cell carcinoma of the head and neck is a lethal disease with suboptimal survival outcomes and standard therapies with significant comorbidities. Whole exome sequencing data recently revealed an abundance of genetic and expression alterations in a family of enzymes known as protein methyltransferases in a variety of cancer types, including squamous cell carcinoma of the head and neck. These enzymes are...
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