Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Histone Lysine-to-Methionine Mutation as Anticancer Drug Target.

Advances in experimental medicine and biology - 1 Jan 2021

Yang Jianhong, Qiu Qiang, Chen Lijuan

Abstract excerpt

Histone modification stands for a vital genetic information form, which shows tight correlation with the modulation of normal physiological activities by genes. Abnormal regulation of histone methylation due to histone modification enzyme changes and histone mutations plays an important role in the development of cancer. Histone mutations, especially H3K27M and H3K36M, have been identified in various cancers such...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Antineoplastic Agents
Share to Glioma
Share to Histones

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to Lysine

Share to Methionine

Share to Mutation

Source

Identifiers

PMID: 33155140
DOI: 10.1007/978-981-15-8104-5_7

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Histone Lysine-to-Methionine Mutation as Anticancer Drug Target.PMID 33155140Read ↗

Histone H3K27M Mutation in Brain Tumors.Semantic proximity Read ↗

Epigenetic-Targeted Treatments for H3K27M-Mutant Midline Gliomas.Semantic proximity Read ↗

Epigenetic Targeted Therapy for Diffuse Intrinsic Pontine GliomaSemantic proximity Read ↗

Role of somatic cancer mutations in human protein lysine methyltransferases.Semantic proximity Read ↗

Oncohistone Mutations in Diffuse Intrinsic Pontine Glioma.Semantic proximity Read ↗

Advanced Pediatric Diffuse Pontine Glioma Murine Models Pave the Way towards Precision MedicineSemantic proximity Read ↗

KDM1 is a novel therapeutic target for the treatment of gliomasSemantic proximity Read ↗

Potential Epigenetic-Based Therapeutic Targets for GliomaSemantic proximity Read ↗

Diffuse midline glioma treated with epigenetic agent-based immunotherapySemantic proximity Read ↗

Advanced Pediatric Diffuse Pontine Glioma Animal Models Pave the Way Towards Precision MedicineSemantic proximity Read ↗

The mechanistic GEMMs of oncogenic histones.Semantic proximity Read ↗

Histone H3G34 Mutation in Brain and Bone Tumors.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.