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Article

Integrated analysis of transcriptomes of cancer cell lines and patient samples reveals STK11/LKB1-driven regulation of cAMP phosphodiesterase-4D.

Molecular cancer therapeutics - 1 Oct 2014

He Ningning, Kim Nayoung, Song Mee, Park Choa, Kim Somin, Park Eun Young, Yim Hwa Young, Kim Kyunga, Park Jong Hoon, Kim Keun Il, Zhang Fan, Mills Gordon B, Yoon Sukjoon

Abstract excerpt

The recent proliferation of data on large collections of well-characterized cancer cell lines linked to therapeutic drug responses has made it possible to identify lineage- and mutation-specific transcriptional markers that can help optimize implementation of anticancer agents. Here, we leverage these resources to systematically investigate the presence of mutation-specific transcription markers in a wide variety...

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Source

Identifiers

PMID: 25122068
DOI: 10.1158/1535-7163.MCT-14-0297

Genes

STK11

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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Integrated analysis of transcriptomes of cancer cell lines and patient samples reveals STK11/LKB1-driven regulation of cAMP phosphodiesterase-4D.PMID 25122068Read ↗

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