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Article

Crystal structure of the WOPR-DNA complex and implications for Wor1 function in white-opaque switching of Candida albicans.

Cell research - 1 Sept 2014

Zhang Shicheng, Zhang Tianlong, Yan Minghui, Ding Jianping, Chen Jiangye

Abstract excerpt

Wor1 (white-opaque switching regulator 1) is a master regulator of the white-opaque switching in Candida albicans, an opportunistic human fungal pathogen, and is associated with its pathogenicity and commensality. Wor1 contains a conserved DNA-binding region at the N-terminus, consisting of two conserved segments (WOPRa and WOPRb) connected by a non-conserved linker that can bind to specific DNA sequences of the...

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Share to Candida albicans
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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 25091450
DOI: 10.1038/cr.2014.102
PMCID: PMC4152732

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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