Article
Fun30 nucleosome remodeller regulates white-to-opaque switching in Candida albicans.
Acta biochimica et biophysica Sinica - 25 Mar 2023
Gao Ning, Dai Baodi, Nie Xinyi, Zhao Qun, Zhu Wencheng, Chen Jiangye
Abstract excerpt
Candida albicans ( C. albicans) is an opportunistic pathogen in humans and possesses a white-opaque heritable switching system. Wor1 is a master regulator of white-opaque switching and is essential for opaque cell formation in C. albicans. However, the regulatory network of Wor1 in white-opaque switching is still vague. In this study, we obtain a series of Wor1-interacting proteins using LexA-Wor1 as bait. Among...
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