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Article

The WOR1 5' untranslated region regulates white-opaque switching in Candida albicans by reducing translational efficiency.

Molecular microbiology - 1 Jul 2015

Guan Zhiyun, Liu Haoping

Abstract excerpt

The human fungal pathogen Candida albicans undergoes white-opaque phenotypic switching, which enhances its adaptation to host niches. Switching is controlled by a transcriptional regulatory network of interlocking feedback loops acting on the transcription of WOR1, the master regulator of white-opaque switching, but regulation of the network on the translational level is not yet explored. Here, we show that the...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 25831958
DOI: 10.1111/mmi.13014
PMCID: PMC4552353

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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