Article
Distinct class of DNA-binding domains is exemplified by a master regulator of phenotypic switching in Candida albicans.
Proceedings of the National Academy of Sciences of the United States of America - 10 Aug 2010
Lohse Matthew B, Zordan Rebecca E, Cain Christopher W, Johnson Alexander D
Abstract excerpt
Among the most important classes of regulatory proteins are the sequence-specific DNA-binding proteins that control transcription through the occupancy of discrete DNA sequences within genomes. Currently, this class of proteins encompasses at least 37 distinct structural superfamilies and more than 100 distinct structural motifs. In this paper, we examine the transcriptional regulator Wor1, a master regulator of...
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