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Article

Myostatin knockout in bovine fetal fibroblasts by using TALEN.

Yi chuan = Hereditas - 1 Jul 2014

Yang Cuicui, Tong Huili, Ma Xinghong, Du Wei, Liu Dan, Yang Yu, Yan Yunqin

Abstract excerpt

Myostatin (MSTN) can negatively regulate the growth and development of skeletal muscle, and mutations of bovine MSTN gene can cause a "double-muscle" feature. To knock out MSTN gene in bovine fetal fibroblast by transcription activator-like effector nucleases (TALENs) and obtain MSTN knockout cell lines, we constructed one pair of MSTN-TALEN vector and transfected into bovine fetal fibroblast cells by PEI and...

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Source

Identifiers

PMID: 25076033
DOI: 10.3724/SP.J.1005.2014.0685

Genes

MSTN

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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