Article
Myostatin gene mutated mice induced with tale nucleases.
Animal biotechnology - 1 Jan 2015
Zhou Fangfang, Sun Ruilin, Chen Hongyan, Fei Jian, Lu Daru
Abstract excerpt
Myostain gene (MSTN) is expressed primarily in skeletal muscle, and negatively regulates skeletal muscle mass; it has been suggested that mice with MSTN inhibition have reduced adiposity and improved insulin sensitivity. Therefore, it is important to establish a fast and effective gene editing method. In this report, we established the myostatin mutated-mouse model by microinjection of Transcription...
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