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Article

SWR1 and INO80 chromatin remodelers contribute to DNA double-strand break perinuclear anchorage site choice.

Molecular cell - 21 Aug 2014

Horigome Chihiro, Oma Yukako, Konishi Tatsunori, Schmid Roger, Marcomini Isabella, Hauer Michael H, Dion Vincent, Harata Masahiko, Gasser Susan M

Abstract excerpt

Persistent DNA double-strand breaks (DSBs) are recruited to the nuclear periphery in budding yeast. Both the Nup84 pore subcomplex and Mps3, an inner nuclear membrane (INM) SUN domain protein, have been implicated in DSB binding. It was unclear what, if anything, distinguishes the two potential sites of repair. Here, we characterize and distinguish the two binding sites. First, DSB-pore interaction occurs...

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Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 25066231
DOI: 10.1016/j.molcel.2014.06.027

Genes

INO80

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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SWR1 and INO80 chromatin remodelers contribute to DNA double-strand break perinuclear anchorage site choice.PMID 25066231Read ↗

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