Article
Coordination of Rad1-Rad10 interactions with Msh2-Msh3, Saw1 and RPA is essential for functional 3' non-homologous tail removal.
Nucleic acids research - 1 Jun 2018
Eichmiller Robin, Medina-Rivera Melisa, DeSanto Rachel, Minca Eugen, Kim Christopher, Holland Cory, Seol Ja-Hwan, Schmit Megan, Oramus Diane, Smith Jessica, Gallardo Ignacio F, Finkelstein Ilya J, Lee Sang Eun, Surtees Jennifer A
Abstract excerpt
Double strand DNA break repair (DSBR) comprises multiple pathways. A subset of DSBR pathways, including single strand annealing, involve intermediates with 3' non-homologous tails that must be removed to complete repair. In Saccharomyces cerevisiae, Rad1-Rad10 is the structure-specific endonuclease that cleaves the tails in 3' non-homologous tail removal (3' NHTR). Rad1-Rad10 is also an essential component of the...
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