Article
The Sad1-UNC-84 homology domain in Mps3 interacts with Mps2 to connect the spindle pole body with the nuclear envelope.
The Journal of cell biology - 28 Aug 2006
Jaspersen Sue L, Martin Adriana E, Glazko Galina, Giddings Thomas H, Morgan Garry, Mushegian Arcady, Winey Mark
Abstract excerpt
The spindle pole body (SPB) is the sole site of microtubule nucleation in Saccharomyces cerevisiae; yet, details of its assembly are poorly understood. Integral membrane proteins including Mps2 anchor the soluble core SPB in the nuclear envelope. Adjacent to the core SPB is a membrane-associated SPB substructure known as the half-bridge, where SPB duplication and microtubule nucleation during G1 occurs. We found...
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