Article
Targeting of the SUN protein Mps3 to the inner nuclear membrane by the histone variant H2A.Z.
The Journal of cell biology - 2 May 2011
Gardner Jennifer M, Smoyer Christine J, Stensrud Elizabeth S, Alexander Richard, Gogol Madelaine, Wiegraebe Winfried, Jaspersen Sue L
Abstract excerpt
Understanding the relationship between chromatin and proteins at the nuclear periphery, such as the conserved SUN family of inner nuclear membrane (INM) proteins, is necessary to elucidate how three-dimensional nuclear architecture is established and maintained. We found that the budding yeast SUN protein Mps3 directly binds to the histone variant H2A.Z but not other histones. Biochemical and genetic data...
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