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Article

A uniform survey of allele-specific binding and expression over 1000-Genomes-Project individuals.

Nature communications - 18 Apr 2016

Chen Jieming, Rozowsky Joel, Galeev Timur R, Harmanci Arif, Kitchen Robert, Bedford Jason, Abyzov Alexej, Kong Yong, Regan Lynne, Gerstein Mark

Abstract excerpt

Large-scale sequencing in the 1000 Genomes Project has revealed multitudes of single nucleotide variants (SNVs). Here, we provide insights into the functional effect of these variants using allele-specific behaviour. This can be assessed for an individual by mapping ChIP-seq and RNA-seq reads to a personal genome, and then measuring 'allelic imbalances' between the numbers of reads mapped to the paternal and...

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Identifiers

PMID: 27089393
DOI: 10.1038/ncomms11101
PMCID: PMC4837449

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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