Article
Endothelin 1 gene as a modifier in dilated cardiomyopathy.
Gene - 15 Sept 2014
Matsa Lova Satyanarayna, Sagurthi Someswar Rao, Ananthapur Venkateshwari, Nalla Swapna, Nallari Pratibha
Abstract excerpt
Dilated cardiomyopathy (DCM) is a myocardial disease of unknown etiology with left ventricular dilatation and impaired myocardial contractility leading to heart failure. It is considered to be a multifactorial disorder with the interplay of both genetic and environmental factors. One of the possible genes implicated in DCM is endothelin 1 (EDN1). The genetic variants of EDN1 may be involved in the pathophysiology...
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