Article
Epidermal growth factor receptor gene polymorphisms, R497K, but not (CA)n repeat, is associated with dilated cardiomyopathy.
Clinica chimica acta; international journal of clinical chemistry - 1 May 2009
Zhou Bin, Rao Li, Peng Ying, Zhang Qiuping, Zhang Lin
Abstract excerpt
BACKGROUND: Epidermal growth factor receptor (EGFR) has been recently implicated in pathological tissue remodelling and sustained remodelling processes can lead to pathological outcomes, such as cardiac hypertrophy in heart failure. Dilated cardiomyopathy (DCM) is the most common form of heart muscle disease, comprising 60% of the cases of identified cardiomyopathy. This study aimed to evaluate the association...
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