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Article

X protein mutations in hepatitis B virus DNA predict postoperative survival in hepatocellular carcinoma.

Tumour biology : the journal of the International Society for Oncodevelopmental Biology and Medicine - 1 Oct 2014

Xie Ying, Liu Shufeng, Zhao Yue, Guo Zhanjun, Xu Jinsheng

Abstract excerpt

Hepatitis B virus (HBV) DNA is prone to mutations because of the proofreading deficiencies of HBV polymerase. The postoperative prognostic value of HBV mutations in HBV X protein (HBx) gene was assessed in HBV associated hepatocellular carcinoma (HCC) patients. The HBx gene was amplified and sequ...

Topics

Adult
Aged
Carcinoma, Hepatocellular
DNA, Viral
Female
Hepatitis B
Hepatitis B virus
Humans
Kaplan-Meier Estimate
Liver Neoplasms
Male
Middle Aged

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Mutation

Proportional Hazards Models

Trans-Activators

Viral Regulatory and Accessory Proteins

Source

Identifiers

PMID: 25034530
DOI: 10.1007/s13277-014-2331-0

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 30 Aug 2026. Prepared record publication-25034530-2026-08-30.1. Manifest publication-graph-cohort-2026-08-30.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 30 Aug 2026.

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