Article
X protein mutations in hepatitis B virus DNA predict postoperative survival in hepatocellular carcinoma.
Tumour biology : the journal of the International Society for Oncodevelopmental Biology and Medicine - 1 Oct 2014
Xie Ying, Liu Shufeng, Zhao Yue, Guo Zhanjun, Xu Jinsheng
Abstract excerpt
Hepatitis B virus (HBV) DNA is prone to mutations because of the proofreading deficiencies of HBV polymerase. The postoperative prognostic value of HBV mutations in HBV X protein (HBx) gene was assessed in HBV associated hepatocellular carcinoma (HCC) patients. The HBx gene was amplified and sequenced, the HBV mutations was identified according to NCBI database ( http://www.ncbi.nlm.nih.gov/genome/5536 ). The...
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