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The oncogenic role of hepatitis B virus X gene in hepatocarcinogenesis: recent updates

20 Feb 2024

Abstract excerpt

Hepatocellular carcinoma (HCC) is the most prevalent form of primary liver cancers with high mortality rate. Among its various etiological factors, one of the major risk factors for HCC is a chronic infection of hepatitis B virus (HBV). HBV X protein (HBx) has been identified to play an important role in the HBV-induced HCC pathogenesis since it may interfere with several key regulators of many cellular...

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PMID: 38464387
DOI: 10.37349/etat.2024.00209

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