Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Precore/Core Region Mutations in Hepatitis B Virus DNA Predict Postoperative Survival in Hepatocellular Carcinoma.

PloS one - 1 Jan 2015

Xie Ying, Liu Shufeng, Zhao Yufei, Zhang Lan, Zhao Yue, Liu Binghui, Guo Zhanjun

Abstract excerpt

Hepatitis B virus (HBV) DNA is prone to mutations because of the proofreading deficiencies of HBV polymerase. We have identified hepatocellular carcinoma (HCC) survival-associated HBV mutations in the X protein region of HBV DNA. In the present study, we extend our research to assess HCC survival-associated HBV mutations in the HBV precore/core (PreC/C) region. The PreC/C region was amplified and sequenced and...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Aged
Share to Carcinoma, Hepatocellular
Share to Hepatitis B

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to Hepatitis B virus

Share to Liver Neoplasms

Share to Mutation

Share to Risk Factors

Share to Viral Core Proteins

Source

Open in PubMed Open full text

Identifiers

PMID: 26208136
DOI: 10.1371/journal.pone.0133393
PMCID: PMC4514880

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Precore/Core Region Mutations in Hepatitis B Virus DNA Predict Postoperative Survival in Hepatocellular Carcinoma.PMID 26208136Read ↗

X protein mutations in hepatitis B virus DNA predict postoperative survival in hepatocellular carcinoma.Semantic proximity Read ↗

Hepatitis B virus core antigen mutations predict post-operative prognosis of patients with primary hepatocellular carcinoma.Semantic proximity Read ↗

Naturally occurring precore/core region mutations of hepatitis B virus genotype C related to hepatocellular carcinoma.Semantic proximity Read ↗

Mutations in hepatitis B virus polymerase are associated with the postoperative survival of hepatocellular carcinoma patients.Semantic proximity Read ↗

Review on hepatitis B virus precore/core promoter mutations and their correlation with genotypes and liver disease severitySemantic proximity Read ↗

Precore mutation of hepatitis B virus may contribute to hepatocellular carcinoma risk: evidence from an updated meta-analysis.Semantic proximity Read ↗

Precore/core mutations of hepatitis B virus in hepatocellular carcinomas developed on noncirrhotic livers.Semantic proximity Read ↗

Precore/core region mutations of hepatitis B virus related to clinical severity.Semantic proximity Read ↗

Detection of hepatitis B virus X gene and PreC promoter mutations from chronic hepatitis B patients in the south of Turkey.Semantic proximity Read ↗

Significance of hepatitis B virus genotypes and mutations in the development of hepatocellular carcinoma in AsiaSemantic proximity Read ↗

Comparison study on the complete sequence of hepatitis B virus identifies new mutations in core gene associated with hepatocellular carcinoma.Semantic proximity Read ↗

Precore/basal core promoter mutants and hepatitis B viral DNA levels as predictors for liver deaths and hepatocellular carcinoma.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.