Article
HPV seropositivity joints with susceptibility loci identified in GWASs at apoptosis associated genes to increase the risk of Esophageal Squamous Cell Carcinoma (ESCC).
BMC cancer - 9 Jul 2014
Yang Ju, Wu Huanlei, Wei Sheng, Xiong Huihua, Fu Xiangning, Qi Zhaozhen, Jiang Qian, Li Wen, Hu Guangyuan, Yuan Xianglin, Liao Zhongxing
Abstract excerpt
BACKGROUND: We previously showed that human papillomavirus (HPV) serostatus was not an independent risk factor for esophageal squamous cell carcinoma(ESCC) in nonsmokers and nondrinkers; however, HPV increased the risk in smokers. METHODS: Here we investigated possible interactions between HPV16 serostatus and three susceptibility loci identified in GWASs at apoptosis associated genes with regard to risk of ESCC...
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