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Article

Two novel polymorphisms in PLCE1 are associated with the susceptibility to esophageal squamous cell carcinoma in Chinese population.

Diseases of the esophagus : official journal of the International Society for Diseases of the Esophagus - 1 Jan 2017

Qu Y, Zhang S, Cui L, Wang K, Song C, Wang P, Zhang J, Dai L

Abstract excerpt

Esophageal cancer is the sixth leading cause of cancer-associated death worldwide. Phospholipase C epsilon 1 (PLCE1) gene was found to be associated with the risk of esophageal squamous cell carcinoma (ESCC) by three large-scale genome-wide association studies (GWAS) in Chinese populations. To evaluate the association between the single nucleotide polymorphisms (SNPs) in PLCE1 gene and ESCC risk, a case-control...

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Share to Carcinoma, Squamous Cell
Share to Epistasis, Genetic

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Esophageal Neoplasms

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Share to Phosphoinositide Phospholipase C

Share to Polymorphism, Restriction Fragment Length

Source

Identifiers

PMID: 27061010
DOI: 10.1111/dote.12463

Genes

PLCE1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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