Esophageal squamous cell carcinoma and gastric cardia adenocarcinoma shared susceptibility locus in PLCE1: a meta-analysis.

doi:10.1371/journal.pone.0069214

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Article

Esophageal squamous cell carcinoma and gastric cardia adenocarcinoma shared susceptibility locus in PLCE1: a meta-analysis.

PloS one - 1 Jan 2013

Mai Ruiqin, Cheng Yabin, Huang Yuanshen, Zhang Guohong

Abstract excerpt

BACKGROUND AND OBJECTIVE: Two recent genome-wide association studies have identified a shared susceptibility variation PLCE1 rs2274223 for esophageal squamous cell carcinoma (ESCC) and gastric cardia adenocarcinomas (GCA). Subsequent case-control studies have reported this association in other populations. However, the findings were controversial and the effect remains undetermined. Our aim is to provide a...

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Identifiers

PMID: 23874915
DOI: 10.1371/journal.pone.0069214
PMCID: PMC3715467

Genes

GCA
PLCE1

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