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Article

Caspase8 rs1035142 G>T polymorphism was associated with an increased risk of esophageal cancer in a Chinese population.

Molecular biology reports - 1 Jan 2014

Yin Jun, Tang Weifeng, Shao Aizhong, Wang Liming, Wang Xu, Ding Guowen, Liu Chao, Chen Yijang, Chen Suocheng, Gu Haiyong

Abstract excerpt

Esophageal cancer is one of the ten most common cancers in the world and has poor prognosis. Apoptosis is considered a fundamental component in cancer pathogenesis. We conducted a hospital-based case-control study to evaluate the genetic effects of 16 apoptosis associated single nucleotide polymorphisms (SNPs) on esophageal cancer development. A total of 380 esophageal squamous cell carcinoma (ESCC) cases and 380...

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Identifiers

PMID: 24464182
DOI: 10.1007/s11033-014-3052-6

Genes

CASP8

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