Article
No association between the SOCS-1 -1478CA/del polymorphism and ulcerative colitis in Turkish subjects.
Molecular biology reports - 1 Oct 2014
Hartavi Mustafa, Nak Selim Giray, Oral Barbaros, Deligönül Adem
Abstract excerpt
Suppressor of cytokine signaling (SOCS)-1 is an essential regulator of many cytokine signaling pathways, including those upregulated in the inflamed colonic mucosa of patients with ulcerative colitis. We sought to investigate whether the functional SOCS-1 -1478CA>del polymorphism is associated with UC susceptibility and its disease phenotype in a Turkish clinical sample. A total of 104 subjects were enrolled in a...
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