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Article

The importance of SOCS1 - 1478 CA/del polymorphism and expression in breast cancer: a case-control study in the north of Iran.

Breast cancer research and treatment - 1 Nov 2023

Paeiz Habibbullah, Salehi Zivar, Mashayekhi Farhad, Saeidi Saedi Hamid, Mirzanejad Laleh

Abstract excerpt

PURPOSE: This project aimed to evaluate the relationship between the suppressor of cytokine signaling-1 (SOCS1) - 1478 CA > del genetic variation and breast cancer susceptibility. Moreover, we investigated the SOCS1 mRNA expression level in cancerous tissues. METHODS: A total of 100 patients with breast cancer and 120 healthy individuals were selected. Genomic DNA was extracted from blood. SOCS1 genotyping and...

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PMID: 37526791
DOI: 10.1007/s10549-023-07070-3

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