The SOCS-1 -1478CA/del functional polymorphism (rs33989964) is associated with gastric cancer but is unrelated to overall survival.

doi:10.1007/s11033-023-08296-6

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The SOCS-1 -1478CA/del functional polymorphism (rs33989964) is associated with gastric cancer but is unrelated to overall survival.

Molecular biology reports - 1 Apr 2023

Hartavi Mustafa, Olmez Omer Fatih, Oral Barbaros, Cubukcu Erdem, Nak Selim Giray

Abstract excerpt

BACKGROUND: In vitro studies have shown that the functional - 1478CA > del polymorphism (rs33989964) of the suppressor of cytokine signaling (SOCS)-1 gene is associated with an altered trascriptional activity. Here, we sought to examine the potential association of this polymorphism with the risk of gastric cancer (GC) and to analyze its prognostic impact on overall survival (OS). MATERIALS AND METHODS: The study...

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PMID: 36781608
DOI: 10.1007/s11033-023-08296-6

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