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Article

Functional polymorphism in the suppressor of cytokine signaling 1 gene associated with adult asthma.

American journal of respiratory cell and molecular biology - 1 Apr 2007

Harada Michishige, Nakashima Kazuko, Hirota Tomomitsu, Shimizu Makiko, Doi Satoru, Fujita Kimie, Shirakawa Taro, Enomoto Tadao, Yoshikawa Mamoru, Moriyama Hiroshi, Matsumoto Kenji, Saito Hirohisa, Suzuki Yoichi, Nakamura Yusuke, Tamari Mayumi

Abstract excerpt

Suppressor of cytokine signaling (SOCS) 1 is an essential physiologic regulator of the IFN-gamma signaling that is crucial to lead appropriate immune responses, and impaired IFN-gamma production is considered a hallmark of atopic diseases. Recent study has shown that SOCS1 is also crucial in atte...

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Source

Identifiers

PMID: 17099141
DOI: 10.1165/rcmb.2006-0090OC

Genes

SOCS1
STAT1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-17099141-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

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