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Article

Evaluation of SOCS5 mRNA and its association with serum IL-12 levels and rs41379147 SNP in various subsets of allergic disorders: A case control study.

Molecular immunology - 1 Oct 2023

Hussain Showkat, Rasool Roohi, Shafi Tabasum, Gull Ayaz, Qureshi Taha Ashraf, Jan Rafi, Shah Zafar Amin

Abstract excerpt

BACKGROUND: The SOCS proteins act as suppressors of cytokine signaling by impeding certain signaling pathways. SOCS5, a constituent of the SOCS family, has been associated with the management of allergic reactions, primarily by impeding the signaling of interleukin-4 (IL-4), which is known to have a cardinal function in accelerating the development of an allergic reaction. The key goal of our research was to...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 37672963
DOI: 10.1016/j.molimm.2023.08.011

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 3 Sept 2026.

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