Article
The SOCS-1 -1478CA/del polymorphism is not associated with colorectal cancer or age at onset in Turkish subjects.
Asian Pacific journal of cancer prevention : APJCP - 1 Jan 2013
Hartavi Mustafa, Kurt Ender, Oral Barbaros, Olmez Omer Fatih, Cubukcu Erdem, Deligonul Adem, Avci Nilufer, Manavoglu Osman
Abstract excerpt
BACKGROUND: Suppressor of cytokine signaling (SOCS)-1 acts as a key regulator of many cytokine signaling pathways and its abnormal expression has been identified in several human malignancies, suggesting potential roles in carcinogenesis. The aim of this study was to investigate any association between the functional SOCS- 1 -1478CA>del polymorphism and colorectal cancer (CC) as well as age at onset in a Turkish...
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