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Article

Associations between STAT3 rs744166 polymorphisms and susceptibility to ulcerative colitis and Crohn's disease: a meta-analysis.

PloS one - 1 Jan 2014

Zhang Jixiang, Wu Jianhong, Peng Xiulan, Song Jia, Wang Jun, Dong Weiguo

Abstract excerpt

BACKGROUND: Many studies have investigated the associations between the signal transducer and activator of transcription 3 (STAT3) in the susceptibility to ulcerative colitis (UC) and Crohn's disease (CD). However, the results remain inconsistent. This meta-analysis determined the risk of STAT3 rs744166 polymorphism-conferred UC and CD susceptibility. MATERIALS AND METHODS: Electronic databases, including PubMed,...

Topics

Colitis, Ulcerative
Crohn Disease
Genetic Predisposition to Disease
Humans
Polymorphism, Single Nucleotide
STAT3 Transcription Factor

Source

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Open in PubMed Open full text

Identifiers

PMID: 25286337
DOI: 10.1371/journal.pone.0109625
PMCID: PMC4186844

Genes

STAT3

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 31 Aug 2026.

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