Article
Association study of polymorphisms in SOCS family genes with type 1 diabetes mellitus.
International journal of immunogenetics - 1 Feb 2006
Ni R, Ihara K, Miyako K, Takemoto M, Ishimura M, Kohno H, Matsuura N, Yoshimura A, Hara T
Abstract excerpt
Suppressors of cytokine signalling (SOCS) proteins play important roles in the negative regulation of cytokine signal. We first searched for polymorphisms in SOCS-1, SOCS-3 and SOCS-5 genes, and examined the association of the polymorphisms with type 1 diabetes (T1D). As a result, we did not find any significant associations between SOCS genes and T1D.
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