Article
STAT4 gene influences genetic predisposition to ulcerative colitis but not Crohn's disease in the Spanish population: a replication study.
Human immunology - 1 May 2010
Diaz-Gallo Lina Marcela, Palomino-Morales Rogelio J, Gómez-García María, Cardeña Carlos, Rodrigo Luis, Nieto Antonio, Alcain Guillermo, Cueto Ignacio, López-Nevot Miguel A, Martin Javier
Abstract excerpt
Recently, the signal transducer and activator of transcription 4 (STAT4) gene has been associated with multiple autoimmune diseases. Interestingly, a recent work showed that the T allele of the rs7574865 STAT4 SNP was associated with inflammatory bowel disease (IBD) in a Spanish population. The aim of the present study was to reevaluate the role of the STAT4 rs7574865 polymorphism on IBD. The present case-control...
Topics
- Adult
- Case-Control Studies
- Colitis, Ulcerative
- Crohn Disease
- Female