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Article

The influence of HLA-DRB1*15 on motor cortical pathology in multiple sclerosis.

Neuropathology and applied neurobiology - 1 Apr 2015

Yates Richard L, Esiri Margaret M, Palace Jacqueline, Mittal Arunesh, DeLuca Gabriele C

Abstract excerpt

AIM: Multiple sclerosis (MS) is a common and heterogeneous CNS inflammatory demyelinating disease. The HLA-DRB1 locus may influence clinical outcome. MS cortical pathology is frequent and correlates with measures of clinical disability, including motoric dysfunction that is a predominant feature of disease progression. The influence of HLA-DRB1*15 on motor cortical pathology is unknown. METHODS: A pathologically...

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PMID: 24964187
DOI: 10.1111/nan.12165

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