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Article

Casting light on multiple sclerosis heterogeneity: the role of HLA-DRB1 on spinal cord pathology.

Brain : a journal of neurology - 1 Apr 2013

DeLuca Gabriele C, Alterman Rose, Martin Jenny L, Mittal Arunesh, Blundell Samkeliso, Bird Shannon, Beale Harry, Hong Lai San, Esiri Margaret M

Abstract excerpt

Clinical heterogeneity in multiple sclerosis is the rule. Evidence suggests that HLA-DRB1*15 may play a role in clinical outcome. Spinal cord pathology is common and contributes significantly to disability in the disease. The influence of HLA-DRB1*15 on multiple sclerosis spinal cord pathology is unknown. A post-mortem cohort of pathologically confirmed cases with multiple sclerosis (n = 108, 34 males) with fresh...

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Identifiers

PMID: 23485854
DOI: 10.1093/brain/awt031

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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