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Article

Polygenic risk scores in bipolar disorder subgroups.

Journal of affective disorders - 1 Sept 2015

Aminoff Sofie Ragnhild, Tesli Martin, Bettella Francesco, Aas Monica, Lagerberg Trine Vik, Djurovic Srdjan, Andreassen Ole A, Melle Ingrid

Abstract excerpt

BACKGROUND: Bipolar disorder (BD) is a genetically and clinically heterogeneous disorder. Current classifications of BD rely on clinical presentations without any validating biomarkers, making homogenous and valid subtypes warranted. This study aims at investigating whether a BD polygenic risk score (PGRS) can validate BD subtypes including diagnostic sub-categories (BD-I versus BD-II), patients with and without...

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Identifiers

PMID: 26047958
DOI: 10.1016/j.jad.2015.05.021

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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