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Article

Association of schizophrenia polygenic risk score with manic and depressive psychosis in bipolar disorder.

Translational psychiatry - 10 Sept 2018

Markota Matej, Coombes Brandon J, Larrabee Beth R, McElroy Susan L, Bond David J, Veldic Marin, Colby Colin L, Chauhan Mohit, Cuellar-Barboza Alfredo B, Fuentes Manuel, Kung Simon, Prieto Miguel L, Rummans Teresa A, Bobo William V, Frye Mark A, Biernacka Joanna M

Abstract excerpt

Bipolar disorder (BD) is highly heterogeneous in symptomatology. Narrowing the clinical phenotype may increase the power to identify risk genes that contribute to particular BD subtypes. This study was designed to test the hypothesis that genetic overlap between schizophrenia (SZ) and BD is higher for BD with a history of manic psychosis. Analyses were conducted using a Mayo Clinic Bipolar Biobank cohort of 957...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 30201969
DOI: 10.1038/s41398-018-0242-3
PMCID: PMC6131184

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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