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Article

Metabolomics of ApcMin/+ mice genetically susceptible to intestinal cancer.

BMC systems biology - 23 Jun 2014

Dazard Jean-Eudes J, Sandlers Yana, Doerner Stephanie K, Berger Nathan A, Brunengraber Henri

Abstract excerpt

BACKGROUND: To determine how diets high in saturated fat could increase polyp formation in the mouse model of intestinal neoplasia, ApcMin/+, we conducted large-scale metabolome analysis and association study of colon and small intestine polyp formation from plasma and liver samples of ApcMin/+ vs. wild-type littermates, kept on low vs. high-fat diet. Label-free mass spectrometry was used to quantify untargeted...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 24954394
DOI: 10.1186/1752-0509-8-72
PMCID: PMC4099115

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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