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Article

Liver fatty acid-binding protein (L-Fabp) modifies intestinal fatty acid composition and adenoma formation in ApcMin/+ mice.

Cancer prevention research (Philadelphia, Pa.) - 1 Oct 2013

Dharmarajan Sekhar, Newberry Elizabeth P, Montenegro Grace, Nalbantoglu Ilke, Davis Victoria R, Clanahan Michael J, Blanc Valerie, Xie Yan, Luo Jianyang, Fleshman James W, Kennedy Susan, Davidson Nicholas O

Abstract excerpt

Evidence suggests a relationship between dietary fat intake, obesity, and colorectal cancer, implying a role for fatty acid metabolism in intestinal tumorigenesis that is incompletely understood. Liver fatty acid-binding protein (L-Fabp), a dominant intestinal fatty acid-binding protein, regulates intestinal fatty acid trafficking and metabolism, and L-Fabp deletion attenuates diet-induced obesity. Here, we...

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Identifiers

PMID: 23921281
DOI: 10.1158/1940-6207.CAPR-13-0120
PMCID: PMC3791217

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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