Article
[No association of glucocorticoid receptor gene polymorphism (rs6190) with unipolar and bipolar disorder].
Psychiatria polska - 1 Jan 2000
Nemec Dominika, Szczepankiewicz Aleksandra, Leszczyńska-Rodziewicz Anna, Pawlak Joanna, Rajewska-Rager Aleksandra, Dmitrzak-Weglarz Monika, Skibińska Maria, Hauser Joanna
Abstract excerpt
AIM: Functional polymorphism ER22/23EK glucocorticoid receptor leads to reduction of its resistance and to increase in its sensitivity to the glucocorticoid that regulate the functioning of the axis hypothalamus - pituitary - adrenal glands. Disturbances in the regulation of this axis are observed in patients with psychiatric disorders. The aim of this study was to demonstrate the association ER22/23EK...
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