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Article

Characterization of a promoter polymorphism in the glucocorticoid receptor gene and its relationship to three other polymorphisms

12 Oct 2004

Abstract excerpt

OBJECTIVE: Sensitivity to glucocorticoids within the normal population is highly variable and partly determined by polymorphisms in the glucocorticoid receptor (GR) gene (NR3C1). We investigated the exact sequence alteration of a TthIIII polymorphism in the GR gene, whether it is associated with glucocorticoid sensitivity, and its relationship to 3 polymorphisms of the GR gene (N363S, BclI, ER22/23EK). DESIGN:...

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Identifiers

PMID: 15521959
DOI: 10.1111/j.1365-2265.2004.02132.x

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