Article
[Gene of glucocorticoid receptor: structure, polymorphism and clinical associations].
Georgian medical news - 1 Jun 2013
Pristupa L N, Kmyta V V, Savchenko O V
Abstract excerpt
The article provides modern information about the structure of glucocorticoid receptor gene and its isoforms, the most common variants of missens and allelic polymorphisms. The polymorphisms N363S, BclI, ER22/23EK and TthIIII were characterized. The relationship of these polymorphisms with physique and metabolic changes, cardiovascular system diseases as well as with sensitivity to glucocorticoids (GCS) was...
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