Article
Glucocorticoid and mineralocorticoid receptor polymorphisms and clinical characteristics in bipolar disorder patients.
Psychoneuroendocrinology - 1 Nov 2011
Spijker A T, Giltay E J, van Rossum E F C, Manenschijn L, DeRijk R H, Haffmans J, Zitman F G, Hoencamp E
Abstract excerpt
INTRODUCTION: The hypothalamus-pituitary-adrenal (HPA)-axis is often found to be dysregulated in bipolar disorder (BD) while stress and changes in day-night rhythms can trigger a new mood episode. Genetic variants of the glucocorticoid receptor (GR)- and mineralocorticoid receptor (MR)-gene influ...
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