Article
Corticosteroid receptor polymorphisms: determinants of vulnerability and resilience.
European journal of pharmacology - 7 Apr 2008
Derijk Roel H, de Kloet E Ron
Abstract excerpt
Why some individuals thrive and others break down under similar adverse conditions, is a central question in the neuroendocrinology of stress related psychopathology. The brain mineralocorticoid (MR) and glucocorticoid receptors (GR) operate in balance to coordinate behavioural, autonomic and neuroendocrine response patterns involved in homeostasis and health. Genetic variants of both the MR and GR have been...
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