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Article

CBP and p300 acetylate PCNA to link its degradation with nucleotide excision repair synthesis.

Nucleic acids research - 1 Jul 2014

Cazzalini Ornella, Sommatis Sabrina, Tillhon Micol, Dutto Ilaria, Bachi Angela, Rapp Alexander, Nardo Tiziana, Scovassi A Ivana, Necchi Daniela, Cardoso M Cristina, Stivala Lucia A, Prosperi Ennio

Abstract excerpt

The proliferating cell nuclear antigen (PCNA) protein serves as a molecular platform recruiting and coordinating the activity of factors involved in multiple deoxyribonucleic acid (DNA) transactions. To avoid dangerous genome instability, it is necessary to prevent excessive retention of PCNA on chromatin. Although PCNA functions during DNA replication appear to be regulated by different post-translational...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 24939902
DOI: 10.1093/nar/gku533
PMCID: PMC4117764

Genes

PCNA

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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