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Article

Acetylation of the human DNA glycosylase NEIL2 and inhibition of its activity.

Nucleic acids research - 1 Jan 2004

Bhakat Kishor K, Hazra Tapas K, Mitra Sankar

Abstract excerpt

Post-translational modifications of proteins, including acetylation, modulate their cellular functions. Several human DNA replication and repair enzymes have recently been shown to be acetylated, leading to their inactivation in some cases. Here we show that the transcriptional coactivator p300 stably interacts with, and acetylates, the recently discovered human DNA glycosylase NEIL2, involved in the repair of...

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Share to Acetylation
Share to Acetyltransferases
Share to DNA-(Apurinic or Apyrimidinic Site) Lyase

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Open in PubMed Open full text

Identifiers

PMID: 15175427
DOI: 10.1093/nar/gkh632
PMCID: PMC434438

Genes

NEIL2

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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