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Article

Exploitation of EP300 and CREBBP Lysine Acetyltransferases by Cancer.

Cold Spring Harbor perspectives in medicine - 1 Mar 2017

Attar Narsis, Kurdistani Siavash K

Abstract excerpt

p300 and CREB-binding protein (CBP), two homologous lysine acetyltransferases in metazoans, have a myriad of cellular functions. They exert their influence mainly through their roles as transcriptional regulators but also via nontranscriptional effects inside and outside of the nucleus on processes such as DNA replication and metabolism. The versatility of p300/CBP as molecular tools has led to their exploitation...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 27881443
DOI: 10.1101/cshperspect.a026534
PMCID: PMC5334244

Genes

CREBBP

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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