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Article

Detection of KRAS codon 12 and 13 mutations by mutant-enriched PCR assay.

Clinica chimica acta; international journal of clinical chemistry - 25 Sept 2014

Chang Ya-Sian, Er Tze-Kiong, Lu Hsiu-Chin, Yeh Kun-Tu, Chang Jan-Gowth

Abstract excerpt

BACKGROUND: The identification of KRAS mutations before the administration of anti-epidermal growth factor receptor (EGFR) therapy of metastatic colorectal cancer (mCRC) has become important. The aim of the present study was to develop a novel technology that can increase detection sensitivity for KRAS mutations. METHODS: DNAs were extracted from colorectal cancer tissues and formalin-fixed, paraffin-embedded...

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Identifiers

PMID: 24863805
DOI: 10.1016/j.cca.2014.05.008

Genes

KRAS
EGFR

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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