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Article

Sensitive multiplex detection of KRAS codons 12 and 13 mutations in paraffin-embedded tissue specimens.

Journal of clinical pathology - 1 Jan 2011

Laosinchai-Wolf Walairat, Ye Fei, Tran Vu, Yang Zhe, White Roxanna, Bloom Kenneth, Choppa Paul, Labourier Emmanuel

Abstract excerpt

BACKGROUND: Colorectal cancer patients harbouring KRAS mutations in codon 12 or 13 do not benefit from current anti-epidermal growth factor receptor (EGFR) monoclonal antibody therapies. Efficient and robust methods are therefore required for routine clinical testing of KRAS mutation status. AIMS: To evaluate a novel multiplex assay for the rapid detection of common KRAS mutations in formalin-fixed...

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Source

Identifiers

PMID: 21030527
DOI: 10.1136/jcp.2010.081539

Genes

KRAS
EGFR

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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