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Article

Detection of mutations associated with isoniazid resistance in multidrug-resistant Mycobacterium tuberculosis clinical isolates.

The Journal of antimicrobial chemotherapy - 1 Sept 2014

Jagielski Tomasz, Bakuła Zofia, Roeske Katarzyna, Kamiński Michał, Napiórkowska Agnieszka, Augustynowicz-Kopeć Ewa, Zwolska Zofia, Bielecki Jacek

Abstract excerpt

OBJECTIVES: To determine the prevalence of isoniazid resistance-conferring mutations among multidrug-resistant (MDR) isolates of Mycobacterium tuberculosis from Poland. METHODS: Nine genetic loci, including structural genes (katG, inhA, ahpC, kasA, ndh, nat and mshA) and regulatory regions (i.e. the mabA-inhA promoter and oxyR-ahpC intergenic region) of 50 MDR M. tuberculosis isolates collected throughout Poland...

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Identifiers

PMID: 24855126
DOI: 10.1093/jac/dku161

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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